I have some new concerns for us to think about as far as using MICROCRYSTALLINE CELLULOSE as a filler in Nature Throid, Westhroid and ArmourThyroid tablets.

I am a Registered Nurse, with an extensive background in physiology. It occurred to me that just as the cells cannot keep out artificial sweeteners, but absorb them as if they were ordinary glucose, and that this wreaks havoc in our cells ability to function, leading to many forms of physical discomfort and illness, that the same thing would apply if we use MICROCRYSTALLINE CELLULOSE as a filler in our Thyroid products. I remembered reading about why Armour stopped working well for many people, even when they adjusted their dosage correctly. The reason stated was that they had started using artificial fillers.

Doing some research I came upon this article, and want to share it here.  It says exactly that: Our cells cannot stop the micro-nano particles from entering them, and once there, these particles, especially from cellulose from wood, which is what Microcrystalline Cellulose comes from, are not able to be absorbed, but float in and out of the cell membranes, and basically clog up tiny places in our bodies, bio-accumulating as we ingest more, and cause background inflammation to rise. Beware of ‘Cellulose’ as a filler in food products. If it comes from “A Vegetable Source” that is OK, if it does not specify, it means it came from, “Wood Pulp” Steer clear of any and all products that use Microcrystalline Cellulose whose source is not indicated.

A couple of excerpts from the article follow:

Nanotechnology: benefits vs toxic risks,

Feb. 1, 2007 George Burdock Functional Ingredients

“Once in the body, some particles have changed the shape or conformation of proteins, creating a protein similar to that produced in Alzheimer’s disease. Changing protein conformation can potentially create new allergenic proteins in organs to which the body could mount an immune response.

While easy entry into the cells of the intestine and target organs can be beneficial, the other side of the coin is that because these particles are so ‘slippery,’ how can they ever be excreted by the body? Because much of our excretory system at the cellular level is based on a cell successfully excreting a substance (as in the kidney) to be flushed away, how can the particle be made to remain in the waste stream if it can so easily gain re-entry into other cells downstream?

While some of the more dramatic examples of actual physical damage are described above, the damage most often seen in response to nano-materials is the generation of reactive oxygen species, resulting in oxidative stress to the biological system.

In oxidative stress, the universal antioxidant chemical in the body, glutathione or GSH, is converted to the oxidized inactive form, GSSH. As reserves of GSH are depleted and the GSH:GSSH ratio lowers, the body mounts a progressively more assertive reaction. The first stage of oxidative stress is to produce special enzymes to detoxify the new invading chemical; if, however, there is no enzyme for this purpose or the human does not have the capability to produce the enzyme, the body progresses into the next stage, inflammation.””



About Emi Miller

Emi Miller has practiced Integrative Holistic Medicine for thirty years. She is a Registered Nurse, Nationally Certified Holistic Nurse, NCCAOM Certified Asian Bodywork Therapist, Licensed Acupuncturist, Doctor of Naturopathy, and an Interfaith, Stephen Minister. Emi is also a meditation teacher and Pastoral Care Counselor. She has been a student of the world's Spiritual traditions for more than fifty years, and blessed to receive wisdom from many Masters and Saints. She is dedicated to helping bring forth unity of the world's religious Ideals, and the reality of the One Creator of All. Besides her writing and studying the sacred religious traditions, Emi enjoys long walks by the ocean, music and theatre, taking journeys and discovering beauty in natural places, and visiting with good friends and family.
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  1. Mary Jane Voorhees says:

    I found your website in curiosity of the ingredients found in Biosil. I have hyperthyroidism with nodules located on the right side of my thyroid. I am not on any meds or homeopathic supplements for this, however because of my hair loss and aging skin, I thought I would try the above product. I noticed the ingredient, microcrystalline cellulose and decided to research whether this was safe, especially for my thyroid. Also, since taking Biosil, I have indigestion. Thank you for your insight.

    • emi says:

      Hi Mary Jane,
      Yes, the Microcrystalline Cellulose has been giving people problems. I am not sure if your condition is still problematic, but I would be happy to discuss it with you by phone. Thyroid is a specialty of mine. Please call me, if you want to discuss this, 704-804-3353.

      • Sharvella says:

        I just order this drug from Garcinoa Cambogia. And I was reading the ingredients and one of them has microcrystalline celluse. So I’m trying to find out is this safe or not. I read that it causes to lose weight.

      • Aline Silverman says:

        A few years ago I suffered very serious reactions to microcrystalline cellulose when the coating of tyroxin was altered.
        I suffered from pink lesions on the skin. However what was worse was what seemed to be brain side effects…ibability to hold my head up…it was very frightening…I stopped the medecine straight away of my OWN accord and I was put on Euthyrox which does not contain micro cellulose…Now I read what are the inactive ingredients of EVERY medecine I take.

        • Emi Miller says:

          Hi Aline, How terrible! I am very happy that you are being thorough and reading every label. This is our task and we have to learn by ourselves, as our MDs for the most part either do not know about fillers or don’t think they are a problem. Thanks for sharing!

      • Ronni Curtis says:

        I was so happy to see your research on Microcrystalline Cellulose. I was introduced to MCC while in college studying Nutrition and Food Science years ago. We were trying to use it as a filler for weight loss product. I have always wondered if ingesting fiber from wood would be as safe as cellulose from other plant forms that are starch-like carbohydrates. Now I know that it’s not safe. Thank you. I thought it would be linked to Celliac, Thyroid problems is just as bad.

      • Charrisse johnson says:

        Hello, I’ve been taking levothyroxine for 14 yrs it suddenly started making me sick and my DR’s don’t believe me they said I have to take it. Im getting sicker and sicker I’m desperate for help and very depressed can you help me please I think it’s the microcrystalline cellulose but I can’t get my DR’s to believe me.

        • Emi Miller says:

          Hi Charisse, I am sorry to hear about your being unwell. Unfortunately from a small contact like this it is impossible for me to diagnose your physical condition, or see what is going on. As far as the Levothyroxine Inactive Ingredients: Microcrystalline cellulose, calcium phosphate dibasic, povidone and magnesium stearate, there are other ingredients that may be causing problems. Yet I can say that there are alternatives for you, should you and your Dr. agree to let you try another form of Thyroid replacement other than solely T4. While my personal preference is WP Thyroid, they are currently not in production. Yet an alternative might be NP Thyroid by Acella that does not contain any microcrystalline cellulose. If it were myself, and I felt that I was getting ‘sicker and sicker’, and my MD was not on board with my reported symptoms, I would seek another physician for assistance. Asking friends and co-workers can be helpful to find out who they are seeing, and who they left. I hope this has been helpful.

    • Claudia says:

      Hi, my name is Claudia. I have a question. I am currently taking some vitamins by Usana. I was reading the ingredients and has Microcrystalline cellulose.. I have mild hyperthyroid and multinodular goiter..is this ingredients bad for my medical problem?I do not know much about all this ingredients but I am starting to become curious about them

      • Emi Miller says:

        Hi Claudia, Thank you for your note. I do not recommend any products with Microcrystalline Cellulose, unless there is no other alternative. We do have alternatives for Vitamins products, and as far as one that would be helpful to you, with your goiter, you may best check with MD… Some conditions of Thyroid cannot take in extra Iodine, and for others Iodine is a good or OK thing. So please do check and see if you can have Iodine before choosing a supplement. I hope this has been helpful.

  2. Marion Addessa says:

    i have a comment i take lorazapam 0.5 and it is manufactured by watson i wonder if ican be allergic to it i also take armour thyroid the coumpounded one i tingle alot and if any one can give me advice i would be thankful

    • emi says:

      Hi Marion,
      While it is not common to have allergies to Lorazepam, it is always possible. Hives, difficulty breathing and more may occur. If you are concerned, please check with your MD or go to the emergency room for immediate assistance. As far as the tingling with Thyroid Medications, yes this can and does occur, with sensitivity to the drug, and dosage. As Armour Thyroid has been reformulated, it includes ingredients that many people have been sensitive to. You might ask your MD if you can try the new WESTHROID PURE THYROID. It is known as: WP THYROID. It only has two ingredients, inulin from chicory root and Medium Chain Triglycerides from coconut. Most people really seem to like it. Hope this is helpful. — Emi

      • Brian says:

        Just get the levothyroxine compounded at a compounding pharmacy along with lactose, if you aren’t intolerant. That’s what I did and had no reaction to my thyroid medication since. Somewhat pricey and insurance likely won’t pay for it, but it’s your health, right? Pay now or pay later? I get mine compounded for right at $30 for a month supply. Shop around. Another CP wanted $60 for a month supply. Actually, the $30 is a little less than what I was paying for Armour, before figuring out what was going on. Armour has MCC also. This stuff got me bad. I don’t know if it was enhanced gut permeability or what, but has affected every organ including nervous system. My skin literally looks like tree bark. Used to have a baby face. Not any more. Cell turnover throughout your system varies and some will likely be reabsorbed, but hoping I’ll quit peeing foam and tiny crystals here in a year or so. I hope.

        • Emi Miller says:

          Hi Brian, Thanks for writing. Yes, many people are allergic or reactive to Lactose, and yet may I recommend to you that if you use lactose as a filler that you bring in the Organic powder yourself, and have the compounding pharmacy use that instead of powder that is from GMO source. I recommend Organic Coconut Flour or Organic White Rice Flour. So many people react to Lacose. — all the best, Emi

          • Vicki says:

            I don’t even know what to do now. Earlier this year I switched from Armour Thyroid and compounded sustained released T3 to compounded Liothyronine/Levothyroxine. Shortly thereafter I came down with a nasty Psoriasis/Eczema type rash that I could not figure out. Kept thinking it was stress or gluten or something and then I finally thought to consider the thyroid med change. The light bulb finally came on and I carefully read the label on the Lio/Levo med. Ingredient #1 is gelatin (the capsule). Ingredient #2 is microcrystalline cellulose…before the Lio/Levo even. So I promptly had myself switched back to Armour Thyroid and had the prescription filled today. The label on the Armour now says ‘Actavis’. When I was on Armour previously, the bottle said ‘Forest’. I now find that Armour thyroid has microcrystalline cellulose in it also, but it seems to be further down the list of ingredients. I also now find that a Progesterone that I’ve been taking for quite some time has microcrystalline cellulose in it, but I have never had any kind of a reaction to that. I guess I will take the new Armour Thyroid for the next 90 days and see if things improve. It’s really awful that there are these sinister ingredients lurking in meds that we need. I’m just disgusted.

          • Emi Miller says:

            Hi Vicki, Yes we are in a pickle, and being pickled. Good that Armour is working for you. Yes, the amount of Microcrystalline Cellulose is down a ways on the list. I developed a rash inside both of my elbows. I was able to find out that it could be from allergies to medications. So I looked into the additives in my thyroid med, the only med I have to take, thankfully, and that started me on the search of filler ingredients. They are far from harmless. Acacia is also in thyroid meds, and is a huge allergen for many. As for what to take, wait a few months and WP Thyroid will again be on the market. I will let this blog known when it is. There are only a couple of ingredients: Chicory and Inulin. All desiccated thyroid prescription medications are blended with lactose, and this is pretty unavoidable. There is Thyroid-Gold from Australia that was very pure from grass fed cows. This January Australia began spraying the fields with glyphosate, and so the grasses are polluted. Yet the Thyroid-Gold was not a pharmaceutical grade, and dosages varied from batch to batch and even pill to pill I have heard. So hang in there, and you can also check on RLC Labs to see when WP Thyroid will be available. Hope this helps!

          • Denise says:

            Hi Emi,
            What a great site.
            I have been following a clean lifestyle for many years, following a nasty bout of candidiasis.
            A wonderful natural health professional got rid of the candida after 2 years of unsuccessful treatment by doctors (who tested me for all sorts but not candidiasis because here in the UK they don’t believe it exists). Although I have kept a toxic free home, eat organic food, only drink my own filtered water etc etc; I have been unable to rid my body of inflammation. I have very bad arthritis in my hands (I don’t eat nightshades or any food that can cause inflammation) so I no longer have pain but they look awful and have limited mobility. I’m also very active.
            I don’t take any medications but I have been taking supplements, as when tested (by natural bioresonance) I am low
            in some vitamins and minerals. I quickly realised that something wasn’t right and started looking at and researching the ingredients. I too discovered that there were many harmful additives, even though they were “natural/organic/whole” ones.
            I found your article when I searched for mcc and I’m so glad that I did, you’ve reinforced what I know and inspired me to try and find out why my body is still so inflamed. I’ve only just found out about mcc so am ditching ALL my supplements (some only contain gelatin, do you consider that to be problematic?)
            I am seriously lacking in B12 and so will continue to use biocare’s liquid methyl b complex (no hcc) as I don’t want to end up having injections!
            Thank you so much for all the information that you share, keep up the good work.
            Kind regards,
            Denise x

          • Emi Miller says:

            Denise, Thank you so much for your kind remarks. I am sorry that you have been dealing with your inflammatory condition for so long. And as you know, once the joints have been ravages by arthritis, there is nothing to be done to correct that. Yet, by eliminating inflammatory stressors, you have been able to become pain free. This is remarkable. I do however have a couple of suggestions for you. 1) I do not know the kind of ‘filtration system’ you are using for your water. Yet water is so important, it is really the foundation upon which all health is based and maintained. I will suggest this, here, even though I have not heard from you, just in case it can help: There is ONLY ONE SYSTEM that can remove all toxins including Hexavalent Chromium 6. And that is Reverse Osmosis. There is one system that I recommend, and without any compensation at all, just I have found through research, for myself, that I feel it is a superior quality. That system is for your kitchen sink: APEC Complete Filter Set for ESSENCE 90 GPD PH Reverse Osmosis 6-Stage Systems (Stages 1-6) https://www.freedrinkingwater.com/ro-90-detail.htm — Yet you will also need a whole house filter, as we absorb toxins in the shower and bath, even more than through food. Aqua Sana Whole House: — 500,000 GALLON RHINO https://www.aquasana.com/whole-house-water-filters/600k-gallon-rhino They also make one of each for those on Well Water. Please be assured I take NO MONEY from either of these businesses… Only passing on my research. — As far as being low in B12… This is so very important. Please do try to add some Organic Chicken Soup to your diet, cooked with the bones, I say this even if you are a vegetarian. Your body is crying out to you for help. B12 as you know is best sourced through animal protein. We do have four Canine Teeth, which means genetically we have been meat eaters, and our DNA is built around this. Living in four season climates our bodies suffer so much on a cold fruit and salad and veggie diet. Even Organic Lamb Stew in Winter Only would be helpful. Not in Summer. Hope this is helpful.

  3. Gayle matthews says:

    What can replace armour thyroid?

    • emi says:

      Hi Gayle,
      Sorry for the delay in answering your post. There is a great Natural Thyroid medication that I am recommending. It only has two ingredients, and no Microcrystalline Cellulose. It is a Relatively NEW PRODUCT by Westhroid, so make sure you ask your MD for it specifically, as the OLD WESTHROID still has ingredients that have caused many problems. It is called: WP THYROID. That stands for WESTHROID PURE. The added inactive ingredients are clean: inulin from chicory root and Medium Chain Triglycerides from coconut. IT does have some Lactose in it as this comes in all porcine powdered Thyroid, yet we are told that its form is hypoallergenic. People who are Lactose intollerant seem to have no problems with it. I hope this is helpful! — Emi

      • Francis says:

        Thank you Emi your article is so helpful. Could you please tell me where I can buy Westhroid Pure?

        • Emi Miller says:

          Hi Francis, OK, you can have your MD order it for you from any pharmacy, such as Walmart, Walgreens, Rite Aide. They have to ask for: WP Thyroid. If they ask for Westhroid Pure you are likely to get the original Westhroid, which has fillers we do not want. That is why they made WP Thyroid. I hope this helps!

  4. Perry W. Keith Austin says:

    Microcrystalline Cellulose should not be used in products we consume.

    • emi says:

      Hi Perry,
      I agree totally. It’s source is typically wood pulp, and ordinarily our cells can keep out the molecules of wood, as they are indigestible. Yet, when they are made microscopic, they can interfere with our cells normal functions, as the cell can neither keep them out, or dissolve them. Especially if they are included in a hormone formula that the cells recognize and NEED. The hormone enters the cell membrane and cannot help but also take into itself the microcrystalline cellulose. We found this was true with Microcrystalline Calcium products as well as Microfiber Pantyhose. In the latter the microparticles became lodged in women’s legs, causing hive-like welts, and some of these particles were actually absorbed into the system. Please read the labels of these new dusting cloths, and don’t buy anything at all that says it contains micro particles. — Emi

      • Aideen says:

        Is there any calcium supplement, preferably also containing vitamin D3, that is free from dangerous ingredients ? The one I’ve been taking contains aspartame. I’ve just bought another one – still sealed – but it contains microcrystalline cellulose, which your site is telling me is bad. Please help ! ! I’m told I have osteoporosis. I would be very grateful for as much detailed advice as you have time to give.

        • Emi Miller says:

          Hi Aideen, Oh it is sooo hard to find good supplements. They all seem to have one or two fillers or ingredients we don’t want. Here is one of the best ones I have found: Blue Bonnet Liquid Calcium Citrate, Magnesium and Vitamin D3. It has Xanthan Gum in it, which can be an irritant to the intestines, yet in each dose of the Cal/Mag/D3 it will probably be too small to do harm. Blue Bonnet also makes an EARTH SWEET® CHEWABLES CALCIUM MAGNESIUM & VITAMIN D3 TABLETS (NATURAL VANILLA FLAVOR)– it has stearic acid in it, which we don’t know the source, yet Blue Bonnet does not use GMOs in their products, and since they are Kosher, if the fat source is animal it has been raised well and has died painlessly. They are very reputable. Calcium lactate is not the way to go. Calcium Citrate is easily absorbed. Hope this helps your search. And remember: We are NOT wanting to take high doses of Calcium supplements anymore. We are to try to get absorbable calcium from our foods, meaning greens and fish and seaweeds are great sources. Dairy is not an absorbable source. And too much of the wrong form of calcium causes hardening and brittle bones. As well as too much protein. Please take care not to take too much calcium by supplement, even a good kind. Exercise, sunshine, and lots of veggies and fruits in season. Chicken and turkey rather than beef. Cut down dairy. They have found that we in the US have high rates of osteoporosis because we eat too protein. And please about the medications that say they deposit calcium in our bones. Read the adverse reactions carefully before deciding to take them. Hope this helps! 🙂

  5. Stephanie says:

    I can see what you’re saying about the dangers of Microcrystalline cellulose being used in Thyroid medications because these medications are used on a daily basis but what if it’s only used in probiotics?
    Not on a daily basis, but just to replace good bacteria that has been lost after using antibiotics?
    The reason for asking this is because I’ve been advised in the past that probiotics was intended to do just that, but Micocrystalline Cellulose is one of the ingredients in probiotics and because of this there are concerns for using this product on a daily basis.
    Even though I have been advised that this would be good to use on a daily basis for the body to keep good bacteria in the system to help the intestines I have concerns that the body would then become dependent on the use of probiotics.
    Being advised that probiotics would however replace the good bacteria lost after taking antibiotics in the intestines quicker than ingesting yogurt because it has a ton more good bacteria.
    Is it really better if it has Microcrytalline cellulose as an ingredient (actually the main ingredient).
    If it is only used to JUST replace good bacteria for TEMPORARY use would it still have the same effect to the body as it has been stated in this article or does that only apply to regular and/or daily use?
    Does this make sense?
    Thank you for reading and I would appreciate your response.

    • emi says:

      Dear Stephanie,

      Thank you for this inquiry. When we look at our gut and see the 1,000 plus kinds of good bacteria that live there, and daily help us to keep healthy, we understand that antibiotics, which kill good and bad bacteria, definitely interfere with our normal flora. While yogurt can be helpful, without any added microcrystalline cellulose, it certainly would not be good for us when it is present, and I see no reason for it to be included in yogurt, except by companies looking for a cheap filler. On the other hand, there is potential harm from even ‘natural, organic’ yogurt, whether we are on antibiotics or not. And that is that when we look at traditional yogurts, and see how they were very effective at keeping people healthy, we will see that they were made in someone’s kitchen, just by taking a couple of tablespoons from the last batch of yogurt, and adding this into their new batch, inoculating it thusly with the bacteria from the old batch.
      In those days there were not billions and billions of 4-10 kinds of bacteria artificially added as we do with today’s yogurts. And yet, they worked great. In our culture we tend to think that more is better. In fact, people want to buy the products that have the most. This is NOT healthy for our gut flora… adding billions of a small number of live bacteria, several times a day, day after day, these bacteria, though helpful in small quantities, have the potential to outnumber our good bacteria, and we will have created an imbalance all by ourselves.

      A better choice when we are on antibiotics is TRADITIONAL, 2-3 YEAR AGED MISO. Miso contains a broad spectrum of bacteria, and has been shown to even be effective on Cancer Cells. This is living bacteria, and I have found it to be much more powerful than taking acidophilus/bifidus capsules, or yogurt. I like MISO MASTER, ORGANIC MISO. Of course if a person has an allergy to any of the ingredients in MISO that presents another situation. Hope this was helpful. — Emi

      • Debra Goring says:

        Wow, that is such a different take on the use of probiotics! I’ve always read that they are good to take, espy if on antibiotics. It’s good to hear this information from someone who works in the industry of getting people well (rather than selling products I guess), so thanks for this valuable information. This post was 2016, not that old, does the info still stand? PS I’m lucky enough to be a regular user of miso (Clearspring brown rice miso, which has been aged, they say, for ” 6 months during a hot summer period in certain prefecture to 18 months in colder regions.” So it doesnt quite classify as “TRADITIONAL, 2-3 YEAR AGED MISO.” but a good make. I will look out for the 2-3 year aged ones now. :O)

        • Debra Goring says:

          Or, from what you are saying, it might be good to make my own yogurt… another thing to add to the list of to-dos! :O)

        • Emi Miller says:

          Hi Debra, Good you are looking into aged Miso. Yes, the info still stands. Traditional diets and remedies have stood the test of time, eh? Other forms of fermented foods have been used to supplement the diets in traditional cultures, as an aid in digestion. Too much can irritate the digestive tract, so use in moderation. Miso was kept inside homes, and a common place was under the bed, where it was stirred now and again, and the mold removed over several years. It was not deliberately heated to reduce the natural curing time. Good to hear from you!

  6. Samudra Leitan says:

    I am pleased to xome across thus information. I was worried to notice that this cellulose compound is in most supplements.

      • emi says:

        Hi Samudra,
        Yes, it is very unfortunate that at this time many products have unhealthy fillers. This is just one, but if you see the word, Cellulose, take note that the FDA has approved companies the right to use the word when they are using Wood Pulp as a filler. This and the various gums, including XANTHAN GUM, which has been irritating the lining of the intestines, and causing even more problems with many who are Gluten Intolerant. Thank you for writing, and please keep reading labels. Companies that we thought were safe and we no longer check their labels, decide to change their ingredients, or have been sold to companies that change their ingredients and we don’t realize we are no longer using a product that we felt good about using. One example is the recent addition of Sodium Lauryl Sulfate, Sodium Laureth Sulfate to 7th Generation Laundry Soap. This ingredient is listed as toxic on the Environmental Working Group’s website, and has been shown to: damage cell membranes, possibly cause hair loss, is linked to skin and eye irritation, organ toxicities, developmental & reproductive toxicities, neurotoxicity, endocrine disruptions, ecotoxicological, and biochemical or cellular changes, and possible cell mutations and cancer. https://www.ewg.org/skindeep/site/about.php# Hope this is helpful — Emi

  7. Scott green says:

    Dear nurse. I’m currently taking clonzapam 0.5 MG and trying to slowley taper off the drug. My question is how can I get all of the microcrystalline cellulose out of my cells, organs and body? Is there a internal rinse so to speak? Thank you !

    • emi says:

      Hi Scott,

      Yes, we do want to cleanse our system, and not just from one or two toxins, but to the many thousands of toxins that assault us daily. The remedy is the same: Make your home as healing an environment as possible. Including water and air filters that are appropriate, beds and bedding, including pillows, all cleaning and personal products, all food organic, clothing natural fibers. Getting rid of all mold, and allergens from your foods, through testing, and developing a Healing Diet, Herbal Remedies and Supplements that are designed for your current condition, Diet Plans that incorporate your current allergens and season, and, if needed appropriate Body Work Therapy that will assist in healing the vibrational tone of the system, appropriate physical exercise and meditation, prayer, breath techniques.

      When all of these are in place, and three months – one year of cleansing, the body’s cells will have been replaced with new and healthier cells, and you will feel very much better. Of course all those in your family unit will also have benefitted.

      I hope this was helpful. I do not know any other way to clean and refresh the body other than following all of these steps together, at one time, in our most toxic and polluted world.

      Thank you for the opportunity to reflect in this way,


  8. HK says:

    I don’t have a thyroid issue, but I found this site while researching the ingredient microcrystalline cellulose. I have recently been diagnosed with a seizure disorder and placed on first Zonegran, and I had a terrible reaction. My entire mouth broke out in ulcers and I couldn’t eat for over 2 weeks. I ate nothing but plain yogurt and drank almond milk with a protein vitamin powder in it. Next, we weaned me down from the Zonegran and added Qudexy XR. It appears that I am again having the same reaction, my mouth is starting to have several severe ulcers again and feels as if it is on fire. I have been free of the Zonegran for 5 days. I don’t know if it is still in my system, of if it is the new medicine causing the ulcers, but they aren’t getting better and feel as though it’s getting worse. I am so frustrated. I researched the ingredients in both medications to see if there was a common ingredient and the only thing I found was an inactive ingredient called microcrystalline cellulose. I just wondered if you had ever heard of anyone having this type of reaction to the additive before? It’s a long shot, but I am tired of switching medicines and having the same result. I just wish I knew what to avoid next time.

    • Emi Miller says:

      Hi HK,

      I can’t answer as to your seizure disorder, and what is the best medication for you. I have done a little research and found that Qudexy does list mouth sores that can be severe, and so Zonegran may also have the same effect for you. Also, amphetamines are often prescribed with anti seizure medication, and they have mouth sores listed as a side effect, as well. I can say that sores in the mouth traditionally indicate irritation in the stomach lining, and there is listed spleen involvement as well with these medications. So, yes, the sores I believe can be from your medication, and also can be made worse from stress, or rough foods, such as hard corn chips, raw veggies, hot, spicy foods, too much acid in your diet. But since they started with your medication, it looks like this has at the least made your condition worse. You can try a bland, soft diet without any dairy or red meat, or whole grains, no coffee and no sodas, and only organic foods for a couple of weeks and see if this helps. Yet, if it were me, I would alert my MD that I wanted to try yet another drug, due to the side effects. The seizure medication that seems to have the least side effects, though it has potentially a lot as well, is an older medication, called Dilantin. I can’t know of course if this one would work for you, but I would ask your MD if you could try this one, if possible, and see if it helps your mouth sores. Still I encourage you to try the above dietary changes as well…they will help to heal your mouth and stomach lining after you change your meds. You can also try slippery elm lozenges, chamomile tea… More specific herbal remedies need to be provided by your herbalist, or Natural Medicine practitioner. Good luck!

      • Shilah Anderson says:

        Shalom, Emi, and thank you for sharing your wisdom !!!! I had Hashimoto’s Thyroiditis for about 10 years and the Creator led me to give up gluten, and then my body healed almost overnight. So I can sympathise with the people here who have thyroid issues, “been there” myself. I try to avoid man-made medicines as much as I can, but have found microcrystalline cellulose in my capsules of Goldenseal!!! aurgh — it’s one of the few antibiotics I do take, & I presently have a sinus infection! I ran out of the bottle of pure Goldenseal root, and while waiting for another to arrive I bought a bottle from walmart (oy….) took one or 2 capsules and felt terrible ! now I know why! 🙁 so I’m “making do” with diffusing plenty of Thieve’s Oil… I have heard to an Essential Oil that helps epilepsy; I don’t know if it would help HK, above, but maybe????…I found this list of oils to consider and oils to avoid, but of course HK will need to do their own research. https://www.pinterest.com/pin/319966748514409284/ I live in Minnesota where many have found medical cannabis to be what they needed…. Just wanted to say THANK YOU, Emi, for explaining why my cheap substitute Goldenseal made me feel so awful; and maybe to contribute a little something for consideration. Truly the Creator knows best what we need. Shalom.

        • Emi Miller says:

          Shalom, Shilah, Thank you for writing, and for the article on Essential Oils to help epilepsy. I am not a favor of essential oils being inhaled or taken internally. I am sure this will cause some to write contesting my statement and belief. However, I have personal and patient experience to relate. And that is that our bodies cannot break down the oils in the concentrated form that we receive them. Not only are they unable to be utilized by our bodies, when inhaled regularly, by simple inhaling or by infusion the tiny droplets become an irritant to our nose and throat, and lungs, becoming lodged on the surface of the delicate inner skin, and as it is an oil, the water of our bodies cannot break it down, or wash it off. It is as if you put oily vasoline on your hands, and tried to rinse it off with only tepid water. It sticks, and does not wash off. We do not have HCL in our nose as we do in our mouth and digestive system. This plus bile from our Gall Bladders is what breaks down oils that we ingest. So you may think that in capsules essential oils may work. Yet the property of the oils as a carrier for the beneficial properties of the plant’s essence, does not afford it the ability to attach itself and then to enter the cell. Rather, the best way to take herbs and plant essences, is to ingest them through teas and tinctures and capsules that are vegetarian, with organic herbs being the only way to be certain all of the benefit is going to be used to help us. — As to your issue with Goldenseal Root. I am not certain why you were taking it, yet may I recommend you try Herb Pharm’s Goldenseal Tincture the next time you want to use this herb. Tinctures are immediately available, and without any need of fillers. Herb Pharm only uses organic or wild sourced herbs. I hope this has been helpful. — all the best, Emi

        • Emi Miller says:

          Hi Shilah, Thanks for writing! So there is a form of goldenseal that I like. It is a tincture by Herb Pharm. I like Herb Pharm’s tinctures very much. First tinctures are best for absorption, and decrease or eliminate the mold factor of herbal remedies. And the level of purity and strength, and consistency of potency has never failed with Herb Pharm since I have been using them, in 1986. Yet, may I recommend another herb that may be helpful for your sinus infections: Eyebright Nettle. I again would use Herb Pharm, along with daily steaming, with a towel over 4 quarts of boiled water, two to three times a day, for 10 minutes total, you can take a breather now and again, lifting your head up from the pot, and uncovering your head if it is too hot. No burning of the face is desired! Then have a wash cloth handy, and soak in the hot water, and apply over the affected areas of the face until the water feels cool. Also, as far as your home is concerned, make sure there is no mold. We can speak about this if you like by SKYPE. Also, no dairy, no sugar, no fruit juices, no chocolate, no alcohol. :-). Yes, steamed greens in abundance, organic, and a completely organic diet. This is NOT complete as there will be other herbs and treatment suggestions depending on your full evaluation.

          I hope this helps,
          all the best,

  9. Tracy says:

    Do you have any info / warnings on the use of Serrapeptase? I see one of the ingredients is microcrystalline cellulose.

    • Emi Miller says:

      Hi Tracy, sorry this is delayed. I am not familiar with Serrapeptase, but after looking into it, I would not take it myself. We have not got enough clinical trials about this drug to satisfy me. It seems to increase bleeding, and it is only for short term use, up to 4 weeks. This should tell you something important! As far as Microcrystalline Cellulose as a filler, I would avoid that at all costs.

  10. shai says:

    Thank u so much I started to use recently
    B complex because I wanted to improve my
    Life ,I decided to Google some of the additives
    Ingredients inc microcrystalline cellulose and
    After using it for some time got very worried when I red what u wrote but on other hand
    Was very happy that I found that data
    And know not to use it anymore I recently threw away some c vitamin after learning some
    Harmful effect of some swittner it had in it
    And bought pure vitamin c instead(hope it’s
    Fine)I going to do the same here and more
    Then that telling that I can clean back
    My cells if I stop using it u gave me hope.
    happy to find u another one angel.:)

  11. Maren Roman says:

    The article that you cited is on nanoparticles (“nano-sized particles”) in general. Whether nanoparticles enter the cells in our body depends not only on size but also on the chemical properties of the particles. The surface of our cells is negatively charged and lipophilic (fat-loving). Nanoparticles that have negative charges on their surface will not be able to get near our cells because of charge repulsion. Nanoparticles that are lipophilic may be able to squeeze into cells directly through the cell’s surface (the phospholipid membrane) but hydrophilic (water-loving) particles like MCC can only enter cells via special mechanisms. You can think of these mechanisms as shuttles that require specific keys. Determining whether MCC particles can use these shuttles is tricky because for most detection methods the particles would have to be modified to allow detection by e.g. a fluorescence reader. The modification will affect their chemical properties and therefore may affect their cellular uptake rate and mechanism. But general statements about nanoparticles are often meaningless unless they pertain solely to the particles’ small size, as this is something that all nanoparticles have in common.

    • Emi Miller says:

      Hi Maren, Thanks for writing. Here are just a few of many links for you to explore… Perhaps you have other studies you would like to share? I welcome your feedback!

      The current research demonstrates how difficult it is to map out the health effects of nanoparticles. Since the number of possible combinations of nanoparticles and various biomolecules is immense, it is practically impossible to research them systematically. Even if a certain nanoparticle does not appear toxic, the interaction between this nanoparticle and other compounds in the human body may cause serious problems to cell functions. Further, combining nanoparticles with toxic substances poses even more serious questions. Be wary of products which tout the use of nanoparticles. This is yet another reason why consumers need to demand natural, organically grown ingredients in products.

      Learn more: http://www.naturalnews.com/024916_nanoparticles_research_health.html#ixzz4UNoaNBFu
      Nanoparticles can damage DNA, increase cancer risk — http://phys.org/news/2007-04-nanoparticles-dna-cancer.html
      Do Nanoparticles in Food Pose a Health Risk? A new study reveals that nanoparticles are being used in everything from beer to baby drinks despite a lack of safety information — https://www.scientificamerican.com/article/do-nanoparticles-in-food-pose-health-risk/

  12. independz says:

    good article but you have to remember that this is not just the microcrystaline all the celluose today being used in nutreceuticals as well as pharmaceuticals are all nano~ the methods are going to a “nanodelivery” and this is also being utilized in vaccines and in alot of health supplements which when consumed aggragate and agglomerate and morph and get activated with almost any form of frequency and it begins it’s assmblying and as a result it densifies even more
    augmentinforce.com has several links on the topic and yes you can get this out but with great difficulty

    • Emi Miller says:

      Hi Independz, Thank you for this comment. I am aware of many of the ways that nanoparticles are being used today. And the little research that has been done. We really don’t know what we are messing with here. Do you remember the problems with women’s legs from wearing micro particle stockings? The particles were getting into the skin, and causing rashes. They are using micro particles for making socks, cleaning rags, towels and more. I hope this information can reach people before they buy and use these items.

  13. Cathy F. says:

    Hi Emi, just came across your info on microcystalline cellulose. Could this ingredient cause high blood pressure .? My pressure seems to get higher after taking Solgar vitamins which have that ingredient.

    • Emi Miller says:

      Hi Cathy,
      Sometimes it is a combination of medications that cause elevations in blood pressure. Microcrystalline Cellulose has been implicated in the public arena as a causative factor. I have found that listening to our body is our most important task, especially when it comes to medications. When you get a strong intuition that something is not working, it is a good idea to listen to that voice. Especially if you have tried to push it aside, telling yourself that your MD has recommended it for you, and you ‘should take it.’ but the feeling keeps coming back. That is your body talking to you. Your MD cannot know this. And if you look at the side effects you will probably find your symptom among them, but even if not, it is a good idea to listen… if possible. Often there is another medication that can be chosen with the physician that will work as well, and will not be harmful.

  14. I had Graves. Did i-131 and now in hypo. I started with Naturethroid and by the time I got up to 97.5mcg

    I broke out in hives all over my arms and back side. The next day when I woke, I noticed my back side cleared. It was three week into taking the medicine. I immediately sought my physician who gave me a shot of benadryl because she said she could still see hives I couldn’t see (I am medium skin toned).

    I got put on Levo but had not luck. So I switched to WP Thyroid. I ran out within two weeks because I doubled my dose and went to pharmacy for a refill. They mistakenly gave me Naturethroid and labeled the bottle WP. I did not know. Within days I broke out in a skin rash/hives on my neck, only one side. I went back and get the right kind of medication and immediately started taking it. I only took the Naturethroid for 3 days.

    Now I have this rash on my neck that has been here over a week (nearly 2) and it will not go away. I take benadryl but it doesn’t seem to do anything, so I use Calamine Lotion. It takes away the itching. I don’t know how to get rid of this rash. It seems to be healing I think, the skin is really dry there and is peeling like, but still red. The skin is not raised in welts like the first 2 days. I’m wondering could it be from too much stress or this one particular filler Microcrystalline Cellulose? I looked up all the other ingredients and this one seems to be linked to tons of thyroid posts.

    Dessicated thyroid makes me feel good, Levo does not. Don’t if it’s too much T3 or simply Microcrystalline Cellulose filler. If it was the filler shouldn’t it have disappeared right away like before as soon as I stopped taking it? Any advice?

    • Emi Miller says:

      Hi Jasmine,
      I cannot be certain that this second rash you have is from the WP Thyroid, or a leftover from the hypersensitivity that you had from the Nature-throid, which does have microcrystalline cellulose, and other ingredients that may bother you. The reason is that in your post you say you started WP Thyroid on the heels of the Nature-throid. I do not think that this rash was from stress alone. You may have an allergy to pork, or dairy, or hickory, or acacia, all of which are present. Hoping by now you have settled on something that is working for you. There is a possibility of a T3 medication, Cytomel, that does not come from an animal, and that when combined with a T4 medication, like Synthroid, seems to work pretty food for sensitive people. Hope this is helpful.

  15. Jess says:

    I found this website by researching microcrystalline cellulose, because it is used in an appetite suppressant pill I wanted to purchase. I need help in this area because sometimes its as if my body doesn’t feel full, and especially for 2 weeks before my cycle..I get really hungry. However, this ingredient (like countless others I’ve ruled out), sounds dangerous. Would you happen to know of anything safe that would cause the “full” feeling? Thank you!

    • Emi Miller says:

      Hi Jess, Around the time of a woman’s cycle appetite increases, this is true. I have found that keeping apples handy helps. The estrogen level drops, and many women crave chocolate at this time. This is for one reason because chocolate contains a form of estrogen, and we like to have it. So another thing that I have done is to keep a bag of chocolate chips (organic) in my freezer. I note that just one or two small handfuls slowly chewed, is all that is required to satisfy that urge… It also may come around the middle of the month. As far as the microcrystalline cellulose goes, try to stay far away from any products that contain it, and seek a substitute.

  16. Ricardo says:

    I am a 76 year old Chicano man. For the last 25 years I have been taking Oyster Shell Calcium 500 mg plus Calcitrol (vit.D) for my hypoparathyroid condition (low calcium) which doctors do not what brought it on. I my 30’s I started feeling muscle spasms. After several visits to doctors who were could not tell the reasons for my muscle spasms, I went to an internal medicine doctor who took a calcium blood count and told my calcium count was around 6.5 and needed to be at least 9. Then he referred me to an endocrinologist who put me on calcium and Vitamin D(calcitriol) to increase the calcium level. Since I am a veteran I have been going to the veteran’s hospital for treatment since the 1980’s. I always check the ingredients on whatever I foods I buy, but it never dawn on me to check the ingredients on the calcium tables I take along with (calcitriol). I had my appendix taken out 2 years ago and in the x-rays of my stomach the doctor notice a small cyst on my left kidney around 1.3 centimeters round. Two months ago it had grown to 2.7 centimeters. It is unknown whether it is cancerous or not. I tried to get the doctor to do a biopsy of the cyst but he told me it is to risky for it could spill whatever that means. He doesn’t fell it is cancer but if is he said there only one percent chance that it could spread. He then gave me three options: surgery removal of cyst; freezing of cyst; or further observation of the same.
    Now I started thinking how I got that cyst. I tried to eat as healthy as possible, and I take Vit. C 1000, Vit. E 1000, Salenium, Vit, B100, and green tea, fruits and vegetables. I then look at the ingredients on the calcium bottle and saw a lot of fillers and additives which I suspect might have produced the cyst in my kidney. Those ingredients are the following: Maltodextrin, Microcrystalline Cellulose; Croscaarmellose Sodium, Hypromellose; Starch; Magnesium Stearate; Titanium Dioxide; Stearic Acid; FD & C Yellow # 5; FD&C # 1; Butylated Hydroxytoluene; Butylated Hydroxyanisole; Coconut oil; Triacetin; Propylene Glycol; Polyethylene Glycol.
    Now some of these fillers might be harmless like coconut oil but some I believe are harmful like Titanium Dioxide and others. Hypromellose is an artificial tears and Maltodextrin is a wood pulp.
    Please let me know what you think of all this.
    Thanks You
    Mr. Ricardo

    • Emi Miller says:

      Dear Mr. Ricardo,
      Thank you for writing. Oh my goodness, so many chemicals in one product. And then the calcium comes from a source that is oyster shells, and this cannot be absorbed in our bodies. I would recommend Calcium Citrate as the source of your supplement. One of the better companies is: Pure Encapsulations. As far as the cyst being caused by the chemicals in the calcium supplement you have been taking. This is probably not the causative agent. If it were so, as millions of people take similar products, for years, we would hear about this. However, inflammation in our bodies from air, water, and chemicals in our homes and lives, add up to create a host of physical problems. And it would be difficult to say this is not the case here. If it were me I would get a second opinion about the cyst and then make a determination as to the remedy. But whatever you decide to do, if you would like some help determining a chemical free and healing diet with herbal remedies and other supplements, please call and set up an appointment. There is a lot to be done to make your body healthy. 704-804-3353

  17. donita says:

    I have leaky gut I went to vitamin world and I bought a product called GI natural total digestive wellness with enzmes proniotics whole foods and essential cofactoters.but i also read that it had micro cystaline cellose in it but didnt say how much .i havent used it yet im trying to rebuild my gut with l glusime in high doses along with colstrome and zinc vitamin and on a pleo diet i also use unrefined coconut oil in almost everything i dont know if the product i mentioned in the beginning is good now not knowing a out cystaline cellose.

    • Emi Miller says:

      Hi Harley,
      Thank you for writing. It is amazing that so many supplements that claim to be ‘natural’ contain many ingredients that will further deteriorate the very conditions that they claim to support. I cannot approve of any product including microcrystalline cellulose as an ingredient. As for the rest, without diagnosing a person it is really impossible to say which products or the dosage, will be best for them. So for now, I hope the information about microcrystalline cellulose is helpful. I do phone consults if you would like to set one up, call: 704-804-3353.

  18. Socal says:

    This ingredient is in a skin care exfoliant (first ingredient in the list) i have. Does this ingredient cause harm when used topically?

  19. Nada Dyson says:

    Is there a brand of vitamins you can trust that will have NO xtra fillers that don’t cost an arm & a leg? If one goes on a RAW food change would they not get all the vitamins they need naturally thru the uncooked foods thus no vits needed?

    • Emi Miller says:

      Hi Nada, Thanks for writing! First, we should be careful about raw food diets. They are not for everyone, and they are not for every climate! If we look at people who have leaky gut syndrome, or stomach ulcers, or aged people, or young children before they get their twelve year molars, or people who have autoimmune disorders, arthritis, asthma, migraines, and cancer, many of these people, and more, already have inflammation in the tissues lining their digestive tracts, and if we take whole grains and raw veggies, fruits, nuts, seeds, these will further irritate these already inflamed tissues. Until we can heal these tissues, and bring down the inflammation it is as if we are rubbing sandpaper over a raw scab. This is not helpful.
      And then if we are living in a winter climate, eating raw food, including salads and fruits, and fruit juices, along with raw veggies, these will cool our bodies temperature down internally, and cause us to be out of sync with the season we are in. Then we can easily become ill. Take a look at the Eskimos. If we are trying to live in harmony with nature, and begin a natural lifestyle, then we might look at the diets of our ancestors in various regions of the Earth to see what kind of natural diets they were eating, because, Nada, each area had different foods available to them. No two were exactly alike!
      So what did the Eskimos eat 100 years ago in the winter? Did they eat kale? Avocados? Tomatoes? Raw Fruits or Vegetable Juices? No? They ate bear meat, and whales, and all of the fat and blubber in these foods. No greens. And they were perfectly healthy! No high cholesterol! The cold temperature burned the fat inside them, and they kept warm.
      Yet, if we look at the people who lived in India back then, did they eat Bear meat and whales? No? How about the people in Africa — did they eat the way that the Eskimos ate? No? They ate bananas and coconuts and lots of greens and fish from their fields. How about the Native Americans in the northern U.S. in the winter? Did they eat blueberries in December? Raw salads in January? No? They ate cooked deer and bear, chewed smoked, salted meat, and cooked porridge from stored corn, and root veggies, and other ground grains, and were healthy.
      So, Nada, I don’t know where you live, but if you live in a four season climate, you might be better serving your body if you rotate your diet, and eat cooked veggies and grains and local, organically and pasture raised chickens and fish (and even lamb) to warm you up in the winter, and save your raw,cooling foods for the summer. Just think about what the Native Peoples used to eat in YOUR area, and follow that as your natural diet.
      Or, if you want to keep to a raw diet, then would you please consider moving your body to a warmer year-round climate, where your intellectual ideas will match the climate you are living in? Then you can be healthy! — As far as the vitamins, I don’t think they are needed in the warm months of the year if we are eating well. But in the cold months, if you are coming down with a cold or flu, or anytime that you feel weak, then it is a good idea to take them. I use them as others would use antibiotics. They can be very helpful to give a boost to our immune system used in this way.
      In my opinion so far I have not found any 100% good vitamins out there. All of them have ingredients that are not good for us. The best ones that I have found are not the whole foods ones. By the time they have been processed into tiny pills there is not much benefit to them. And we should chew our veggies, getting them prepared for our stomach with the enzymes that we need to absorb them. With that said, I have chosen chewable vitamins and extra chewable vitamin C for times when I feel a cold coming on. I hope this has been helpful to you! — Emi

  20. Alehia says:

    Hi I ordered elon matrix 5000 for a hair vitamin so many great reviews on it and recommendations from dermatologist. I read that it has microcrystalline cellulose in it and decided too look it up. One week of taking It i noticed soreness in my neck so that’s when I look up the ingredients and came across your site. Have not took anymore since can you recommend a good hair and skin vitamin?

    • Emi Miller says:

      Alehia, The best solution for hair and skin is to find a good nutritionist and look into your diet. Try to get good quality organic foods, and also I don’t know if you are using products that are harmful to your hair… coloring it, straightening it, over drying it, curling it with a hot iron. All of these things will influence your hair, as well as being over emotional, kidney and intestinal conditions, parasites, hormonal deficiencies, anemia, and other illnesses, including of course chemotherapy. So, I am happy that you stopped the product that was making you have a rash. How terrible. Yet as you can see it is difficult to prescribe for you without knowing more of what is going on.

  21. Karen Gardner says:

    Dear Emi, So glad I found your site. I had my thyroid removed in 2000 and took Armour Thyroid and did well. Chewed Chewable Calcium Now it has too much sugar in it. Now the Armour with micro cellulose causes me problems. I just started on WP Thyroid and it is absorbing more than the Armour. After 3 hours I get jittery. Taking Calcium and Magnesium calms it down. I have lost my appetite. Now I see there is micro cellulose in the vitamins. I will research and find Pure Encapulations. I take Cinnamon capsules and Bilberry to keep my sugar down. Now my blood pressure has gone up. Take Enalapril for that and Garlic and aspirin. I am going to try and lower my dose of WP Thyroid since it appears to absorb more to stop jitteriness. Any other advice

    • Emi Miller says:

      Hi Karen, Sorry about being so late in replying.. UGH… life was full before websites, eh? As far as being shaky taking WP Thyroid… I understand. I have found that taking it 20 minutes AFTER BREAKFAST works. AND I take only 1/2 dose in the am… and then the other 1/2 dose about 1 hour after lunch, when the body’s metabolic rate is up enough to deal with the WP Thyroid. It tends to come on like gangbusters. Yet, if you take it after breakfast it comes on slowly and works great. Try that and see if it works. Pure Encapsulations is not the purest out there. There are no absolutely pure vitamins or supplements that I have found. I like Blue Bonnet Chewable Vitamins… We are not taking mega doses anymore, unless there is medical indications for them. We are trying to allow our bodies to get the vitamins from our organic veggies and foods as much as possible. They have found that when vitamin levels are too high that our body shuts down absorbing vitamins and minerals from our food, and this is a problem because we don’t know all of the micronutrients that we need, for one thing, we have not discovered all of them, and for another thing vitamin pills are not living energy. We need living energy to be put into our living cells. Hope this helps!

  22. Bill S. says:

    Wow. You’re good.

  23. Tina says:

    Hi Emi,

    Do you have any recommendations for low T3 (natural if possible)? My NTP has me on Liothyronine sod 5 mcg tab xday.
    My blood work before taking Thyroid meds was:
    Free T4 1.14
    TSH 3.33
    RT3 17.7
    Free T3 2.3

    Thanks in advance!

    • Emi Miller says:

      Low T3 for those with hypothyoidism who have been on a T4 Only medication is the reason folks are moving to Natural Thyroid medications from the T4 meds such as Synthroid and Levothyroxine. I am not familiar with your condition. I can say that if you have hypothyroidism or hashimotos that has been diagnosed, and have been on T4 meds which have left your T3 low, then you might want to try WP Thyroid and see if your T3 can come up. If you feel you want to go this way, just ask your MD for a trial of 3 months on WP Thyroid. Not knowing your condition it is not possible to offer more than this.

  24. Diana says:

    EXCELLENT article and informtion. I get my westroid from a compounding pharmacy and decided to purchase their New vitamin D3. But i just read ingredient was MCC ( microcrystaline cellulosr) and after reading your interesting post of wood pulp and nano particles, no thanks. Im leaving that alone. I found out my prior D3 contained chickory/hickory and I had tingling like itchies that made me crazy. So Im listening to my body.
    Thank you so much for your enlightening post !

    • Emi Miller says:

      Hi Diana, Great work in listening to your body! As far as D3 goes, it has mostly been coming from lanolin. This is NOT GOOD for us. Why? Sheep produce it to keep them dry. Water does not dissolve it. Vitamin D is a fat soluble vitamin, water does not break it down. We have to be careful of the source, and we are finding out that we have been taking too much of it, and people have been becoming toxic. A much better source is the sun! YES! Without sunscreen one inch of skin absorbs 1,000 IUs of Vitamin D every 10 minutes! And it is completely absorbed. Try to spend 15 minutes in the mornings whenever you can out of doors in the Spring and Winter this can be in the afternoons, too. Summer the sun can be too hot from 11:00 am on. However for those who want to take supplements, or need to, a purified Cod Liver Oil is a better source. Arctic Cod Liver Oil by Nordic Naturals is one that I recommend for my patients. There are others you may find and like. Hope this is helpful.

      • Julia says:

        Why is the naturally fat soluble nature of lanolin derived D3 problematic? Many vitamins and nutrients are fat soluble…they are naturally so and always have been. This has always been my understanding of D3. I intentionally take lanolin derived liquid D3 (in MCT from coconut oil) as it seems most natural to me.

        Re: sunlight exposure, I am extremely pale skinned – I always burn, I can only tan a tiny bit (AFTER burning) but mostly I just freckle like crazy. After just 10 minutes in direct sunlight I develop dozens of new freckles and these can take years to fade, if they fade at all. At almost 37, I have been avoiding direct sunlight as much as possible for the last 15+years, much abetted by my nocturnal schedule. My mother was a redhead who had hundreds of minor skin cancer lesions removed over the years and eventually died from a more serious form of skin cancer. But she had a ton of sun exposure and used sunscreen/block (both of which I believe to increase DNA damage from UV exposure, and which I have avoided since childhood). I am quite terrified of UV damage as a result, as well as the freckles and wrinkles which I wish to avoid. Do you think that I/similarly fair people should expose ourselves to sunlight or take D3 instead? There is not all that much sunlight where I live in NW Germany, anyway. How long of daily exposure would I need on overcast days?

        • Emi Miller says:

          Julia, Thank you for your kind words in both of your posts. Yes, I do think that getting Vitamin D from the sunlight is the best way, and most necessary for our bodies. Science has not discovered all of the different beneficial rays that the sunlight contains.We do know that Vitamin D is so very necessary for our bones and health. So, the recommendation is for 10 – 20 minutes per day in sunlight not at peak times. Science has found that one inch of skin exposed to for 10 minutes to direct sunlight absorbs 1,000 units of Vitamin D. Pretty important information. As far as the difference in the fat form of Vitamin D3 from sheep being different from the fat form of Vitamin D3 from Coconut. I think that you will agree that a four legged animal’s fat has been researched to cause increased problems in the human body compared with vegetable sources of fat. And this is because the fat molecules cannot be absorbed as easily. I hope this helps. Please research the importance of natural sunlight. And also research the increased cancer risk for night workers who sleep during the day. This is because the body cleanses itself of toxins, and does tissue building, and repair at night. Nocturnal lifestyles have not historically been a part of the evolution of our bodies…humans sleeping at night crosses almost all societies. So take care trying to avoid one problem that you are inadvertently creating others. all the best, Emi

  25. Gloria says:

    Hey Emi,

    It’s been a while since i don’t eat as much meat as before, i guess i eat 1 time in a month or there were months when i didn’t even eat. So i searched on the internet and found that i probably have a deficient in vitamin B12 (lots of fatigue, loose memory frequently etc..)

    Wanted to purchase it on Amazon, but found that has microcrystalline cellulose in it. I tried searched other brands, but it’s almost everywhere…

    Then i came up to your blog and found this super information, but i still don’t know what to do.

    Can you please advise me? Should i buy in the pharmacy? Liquid one? Maybe more expensive as the tablets, but i guess it doesn’t contain microcrystalline cellulose.

    Thanks a lot!

    • Emi Miller says:

      Hi Gloria, I am not sure what you are wanting to purchase? Of course I am not in favor of Microcrystalline Cellulose. As for not eating meat. We are the only people that have ever been on the planet that could intellectually decide not to eat meat, if we lived in a northern location, where fruit does not grow year round. Not sure where you live, but if you live where there are four seasons, you would do well to eat at least chicken and turkey in the winter. And especially if you are B12 deficient. Many of us come from northern European ancestors, and our DNA is programmed to extract nutrients we need from meat. When we stop it we become ill. Not many people can be vegetarians successfully. If you cannot bring yourself to eat meat, I would ask that you please move to a climate like Hawaii or California, or India, where winter does not come, and the trees give oranges and papayas, mangos, coconuts, guava, avocados and dates and more. There you might be better able to manage. Hope this is helpful to you.

  26. Tammy says:

    This article seems like it was written exclusively for me. I was taking Armour Thyroid after it was reformulated. After being on it for a while I began to have really bad inflammation and my blood pressure began to get high. My doctor couldn’t explain why this was happening. I finally started researching the ingredients in the Armour pill. From the articles I read I determined it had to be the Microcrystalline Cellulose causing my problems. So when WP Thyroid came out I immediately switched over and started taking it. The inflammation is gone since I have been on Wp Thyroid but anytime I ingest anything that has Microcrystalline Cellulose in it I get the inflammation and the high blood pressure back. I also get the same reaction from some of the gums in food. My question is can your body ever get rid of these particles? It is very hard to live in this day and age of fillers and gums. They put them in so many foods and supplements. I have to read everything I eat.

    • Emi Miller says:

      Hi Tammy, I have chosen to use Dr. Bronner’s Peppermint bar soap. There are many soaps that are hand made that may be purer, but for my budget this one is good enough, and makes my skin feel good, not dry, not itchy. I have followed Dr. Bronner’s soaps since the 1980’s. His son has taken over the ship, and is doing a fine job, in my opinion. Organic ingredients, no harsh chemicals. However, for very sensitive skin they make an organic castille olive oil based soap: Dr. Bronner’s Baby Unscented Liquid Castille Soap – 4oz It is a liquid. Check them out… Hope this helps!

  27. Candice says:

    Hi E

    Which soap brand in the former of a bar is safe to use? We changed to pure glycerine soap but it also contains the sodium Laureth sulphate and soduim laurate. I lnow of and we do sometimes use liquid Castille soap but it is expensive and we run through a bottle very quickly as a family.

    Appreciate your input.

    • Emi Miller says:

      Hi Candice, I replied to your post, yet don’t see that reply, so I will answer again. I use Dr. Bronner’s bar soap, Almond. It works for me and has been good for my patients, too. I hope this is helpful.

  28. Bsvdbigrac@aol.com says:

    Why can we not stop the adulteration of our foods by these killer chemicals being added to what God has made for our body? It is all about money!!!

    • Emi Miller says:

      Yes, in almost all cases it is all about money. And so called “Natural” products are no different. Microcrystalline Cellulose is only one, of course. Others abound. Watch out for Almond Milk, they are using gellan gum which has not had long enough human trials, (seven days is not long enough to show inflammation that will over time erode the gut) it has been shown to cause irritation to the lining of the gut in animal studies. And Croscarmellose is made by first soaking crude cellulose, which can be wood pulp, in sodium hydroxide, and then reacting the cellulose with sodium monochloroacetate, which creates sodium carboxymethylcellulose. The sodium monochloroacetate becomes glycolic acid and the glycolic acid creates croscarmellose sodium. And the other gums are also used as thickeners. I have not found a almond milk that does not have these fillers. Let me know if you have. Try to find products that do not use these and many other fillers that are questionable. Check out: http://www.ewg.org/ they have done a great job listing chemicals that are harmful, and why. They do not have all of them, so keep your research going.

    • Emi Miller says:

      Yes, for the most part you are correct, unfortunately. We have to educate ourselves as much as possible, so we can read labels and keep ourselves as healthy as we can in this polluted world. Thanks for writing…

  29. Nelli says:

    Hello.Thank You very much for the info. I found microcrystalline cellulose as a ingredient in a oral hygiene probiotic for children – i give this one to my 4 year old son. Now i am worried. I have tree more bottles of this expensive probiotic. But the health of my child is the most important to me, so I will trow this “STUFF” away.

    • Emi Miller says:

      Nellie, no matter the cost I throw out items that I find have toxins in them myself, and have always done so, keeping my family safe is my most important job. 🙂 Good work!

  30. Salvatore Greco says:

    Hi Emi, my heart doctor just put me on Effient 10mg which contains this microcrystalline cellulose among mant other inactive ingredients. What say you on this medication.
    Thank you
    Sal Greco

    • Emi Miller says:

      Hi Salvatore, Unfortunately it is impossible to comment on a drug that has been recommended for you from your MD for this serious condition. With the thyroid medications, for example, there are other choices available that do not contain harmful inactive ingredients. In this case you and your MD(s) should have a discussion to see what choices are available, and if any of them contain other inactive ingredients. Many feel this a better choice than the older Warfarin, which necessitated weekly blood tests as well as routinely causing vascular breakdown, and bleeding into the skin. I hope that it will work well for you. AND you may also want to look into a natural healer, who specializes in Nutritional support, with approved supplements that may be able to help you to heal, from the inside out.

  31. Rose says:

    Hi Rose, Sorry to hear about your difficulties with Hashimotos. I will give you the link to the companies website. You can call them and check. I am certain that your doctor can call in an RX and get the medication. Their production is down right now unfortunately, as they are in process of moving to a larger facility to handle the huge increase in demand for this wonderful product.


    Thanks for asking!


    Hi Emi,
    I was diagnosed with Early Menopause 7 years ago (I was 33 years in that time), 2 years ago with Hashimoto’s disease, and 3 years ago with Osteopenia.
    I am trying to figure out how to deal with my disease by myself because to be honest the doctors here (Perth, Australia) are very negligent and not always updated.
    All the time I need to told them what to do respect to my Hashimoto’s and other conditions (medication, diet, kind of tests, etc, etc, etc).
    Do you know if in Perth Australia can I get WESTHROID PURE THYROID?

    Thanks in advance for your time

  32. Regina Benton says:

    Hi Emi, I’m a 52 year old female. I take metroprol 50 mg daily for high BP. At 28 I was diagnosed with Fibromyalgia, CF Syndrome. And blood work indicated some kind of autoimmune disease, but they never said what. For 22 years I was on Wellbutrin, nortriptilyne. I weaned myself off all medications (except for the BP med and Lorezpam 2mg) because I was still having chronic pain. My biggest fear and worry is the brain issues I have. I feel as if I have a cap on my brain, I can’t remember a lot of things and and math is another issue all together. Is there anything you can recommend. I do take a magnesium supplement and fish oils. I recently have started to Dr. ST.Amand protocol of Guaifenesin for the treatment of Fibromyalgia. Do you have any wisdom for this.

    • Emi Miller says:

      Hi Regina, Thank you for contacting me. You have had a difficult time for a long time, with your physical health. And it seems you have done some good work already, weaning yourself from the very strong medications that would have had side effects that would bother your condition, in my opinion. You are taking Guaifenesin, and I do not know the dosage or the length of time you have been taking it. Also I do not know if you are following Dr. St. Amand’s dietary protocol that goes along with his FM Treatment. Are you having symptoms now from this? I would not be able to help you unless you become my patient, and we looked at your history, lab work, diagnosis, medications and dosages and diet. If you would like to do this, we would probably need 4-8 visits. Please let me know if this is something you are interested in pursuing. all the best, Emi

  33. Dawn Marie Bond says:

    Dear Emi,
    I was diagnosed with fibromyalgia several years ago, and in a very short time ( 2 months) my pain had become so terrible I could barely manage getting out of bed some mornings. After several trials of various meds, my doctor prescibed Vicodin. I am an RN and had always avoided narcotics, etc. Despite my knowlege of addiction potential, I became addicted to opiate narcotics. After going through a difficult rehab over 2 yrs later, I began snoring so badly my husband could not sleep. I had a sleep study and was diagnosed with severe sleep apnea. A CPAP machine was recommended, but I could not adjust to sleeping with the mask on. I went to an ENT who said I had a deviated septum, and was not able to breathe welll through my nose. After the surgery to repair my septum, I stopped snoring and almost immediately my fibromyalgia symptoms disappeared. A physician later informed me that sleep apnea disrupts our “dream” stage of sleep, and without this deep sleep our body suffers. He said medical research has shown a direct correllation to sleep apnea and fibromyagia! I was so relieved to know that my very painful condition had been caused most likely from sleep apnea from a deviated septum! I have had no fibromyalgia symptoms since nasal septal repair…thank God!!!

    • Emi Miller says:

      Hi Dawn Marie, Thank you so much for writing. I hope that your story will be of help to others who are suffering from fibromyalgia, or sleep apnea. It is really a shame that you had to go through the process of addiction to opioids before coming to a resolution. Yet as we are seeing throughout our country, millions of people are going through this same difficult situation. Once addicted it becomes almost impossible to wean oneself off opioids as well as antidepressants, another common drug that doctors use to ‘treat’ fibromyalgia. The physical and emotional withdrawal symptoms of coming off these drugs are life altering ; I am very happy to hear that you were able to get off the rebound train of abuse! And, of course while we both know that your deviated septum surgery, that resolved your sleep apnea and fibromyalgia symptoms will not work for everyone, yet if it only helps a few, your story will have been well told. Thank you so much for being brave enough to share it with all of us. And though your post does not mention anything about microcrystalline cellulose, which is the article that you are responding to, I have answered your letter under the heading your posted it, so you will be sure to find it. — All the best, Emi

  34. Judith Batt says:

    My compound chemist is presently working on replacing microcrystalline cellulose in my thyroid medication for white rice starch, ……Something I am able to tolerate he says….because he feels the peripheral neuropathy in hands feet and face, irritable body, restless legs, chronic body joint and tailbone pain, (which makes sitting and sleeping impossible), is the result of Microcrystaline Cellulose. My other 5 meds also have it in unfortunately so it means a whole new redo of all. It also caused shocking mood swings. This stuff should be banned, it is in just about everything on the shelf but people dont know about it. My gluten symptoms also have the same excruciating body pain but with diarrhoa added.

    • Emi Miller says:

      Dear Judith, you have been and are going through a very difficult period of illness. There is much I feel I could help you with as you struggle for health. I am not under the impression that all of your symptoms are due to microcrystalline cellulose, and would like the opportunity to look into your symptoms and work with you for a while. Let me know if that is something you would like to do. And yes, it should be banned from any and all medications for a filler, as well as any personal care or other products as a thickener. I am very happy you are going to find alternate medications. As far as using white rice starch, please make absolutely certain that it is organic. — all the best, Emi

    • Emi Miller says:

      Dear Judith, OK, so this is a good start. Yet remember that Rice is high in arsenic, and if you are using Rice Starch, I would recommend that you use Organic White Rice Flour. I prefer Organic Coconut Flour, yet either should be good. As for the rest of your symptoms, so happy you are going off the Microcrystalline Cellulose, yet this may not be the entire answer. There may be other hidden toxins in your life, and also allergies to foods and more. If you are not feeling better in two months after the change, I would be happy to speak with you via SKYPE and review your history and current condition.

      all the best,

  35. Rose says:

    Hi Emi,

    I hope you are well. I would like to know if microcrystalline cellulose is the same than cellulose? Because I could see that almost all my medication contains cellulose.
    I could not find even some vitamins and supplements (magnesium, potassium, complex B, Zinc and Iron) without cellulose that I need to deal with my Hashimoto’s.
    What can I do?
    Thanks a lot in advance

    • Emi Miller says:

      Hi Rose, I am not sure what medications you are taking, yet cellulose is a catch phrase for wood pulp, or other forms of cellulose, unless it specifically says, “vegetarian source”. I cannot say if there are other forms of medications that you could be taking, yet you could check in with your physicians. As far as the vitamins. I am currently recommending “SmartyPants” Children’s Chewables. Check out the ingredients. They are among the few chewables that use methylcobalamin as the source of B12 rather than cyanocobalamin, which is B12 with cyanide, a known toxin. I hope this helps you. Let me know.

      all the best,

  36. Susan Curtis says:

    Hi Emi,
    I have been taking the same dose of compounded Thyroid for several years. I recently move and had to change compounding pharmacies. My Thyroid levels went up and I had a drying of the scalp which was extremely uncomfortable. I check with both pharmacies and found that the new pharmacy used lactose as a filler while the previous pharmacy used microcrystalline cellulose. This being the only difference, I assume based on this article that the microcrystalline cellulose may have caused the thyroid to be less effective and thus the change to lactose made the thyroid medicine more effective. The doctor lowered the dose and my scalp seems to be getting better. My blood work will be done in a few weeks and I’ll know for sure if the thyroid levels are down. Do you think this is a legitimate theory?

    • Emi Miller says:

      Hi Susan, I cannot say for certain what caused your levels to be higher after your move. There may be a change in jobs or a decrease in stress? These and other environmental changes always factor in. In any case, lactose is a common filler for compounding pharmacies to use. I personally prefer Organic Coconut Flour, or for those who may be sensitive, Organic White Rice Flour. With humans being the only animal on the planet who drinks milk after the weaning period, and another animals’ milk to boot, and with GMOs rampant in dairy, and their effects as to influencing and changing our DNA pouring in, and of course the treatment of dairy cows is so horrific, they live only 5 years as opposed to their natural lifespan of 20 years, and they have infections in their teats, are forced to produce 25.000 pounds of milk a year as opposed to their normal 2,000 – 6,000 pounds per year, with pus and blood found in 90 percent of ALL SAMPLES throughout the U.S, I prefer non-dairy sources as much as possible. An excerpt and a link below…

      I hope this is helpful,
      all the best,

      Condemning The Use Of rGBH
      The American Public Health Association and the American Nurses Association are among many medical groups that condemn the use of rBGH. Additionally, Lippman points out that “the American Academy of Environmental Medicine has advised all doctors to recommend non-GMO diets for their patients.” Eerily enough, however, a notable number of those who dare to speak out publicly against rBGH have been harassed, threatened, or fired — and this includes certain FDA scientists, as well as media professionals.

      Got Genetically Modified Milk?
      Avoid any and all dairy products not clearly labeled organic, non-GMO Project Verified, rbGH-free, rbST-free, or artificial hormone-free, including milk, cream, yogurt, ice cream, cheese, sour cream, cream cheese, and butter. Also avoid the dairy derivative whey protein, used in many protein bars and powders. But don’t get all overwhelmed. Just visit the Center for Food Safety to find a super helpful rBGH-free dairy map to guide your way!

      rBGH False Advertising
      You may notice a label on dairy products that reads something along the lines of “according to the FDA, no significant difference has been shown between milk derived from rBGH-treated cows and non-treated cows.” Not true! Federal courts have recognized that milk from cows treated with genetically modified growth hormones is not in fact identical to milk from untreated cows.

      The FDA’s rBGH labeling guidelines were written by Michael Taylor in 1994. At that time, Taylor was the FDA’s deputy commissioner for policy. Not coincidentally, Taylor has worked for Monsanto as well.


  37. Kim says:

    I came across this page while looking up ingredients found in Zyrtec. I have taken this drug for two years and have recently went to see the doctor for symptoms of extreme fatigue, weight gain, intolerance to cold, light headed and sweet taste in mouth. She found that both my cholesterol and thyroid numbers were high. She recommended that I change my diet and come back in 8 weeks. I went on Friday for more blood work and my thyroid levels are even worse. Not sure about the cholesterol levels because I don’t think they tested for that. I did change my diet and was more active, but my weight is still the same. I read horrible stories of people that stop taking zyrtec, but I’m going to stop taking it anyway. Do you think this drug could be responsible for my thyroid levels. I’m a healthy 55 year old female and have never had an issue with my thyroid. I take vitamins daily and wonder if the side effects of zyrtec explain my symptoms. Wondering if you have heard about this before. Thanks for your time. Kim

    • Emi Miller says:

      Hi Kim, Thank you for writing. Weight gain and cholesterol problems are part of the condition of Hyperthyroidism, or Graves Disease. Make sure your MD takes a bloodiest called, TPO, Anti-Thyroid Antibody test, which she/he may already have done. I would further urge you strongly to see an Endocrinologist, if you have not already done so. It is important to consider your next steps regarding your thyroid issues. There is a medication which can be taken to decrease the thyroid levels in your body. This medication has a lot of side effects, and these can strongly impact your life. Plus you may have to keep taking it for a long time, or forever. There are other options available, including surgery and radiation therapy. Yet, we don’t know the cause…is it a para-thyroid condition, cancer, or what? For these questions you would be best to look into a specialist, and Endocrinologist. Thyroid is so very difficult to diagnose and then to treat. There are new blood tests that MDs are not yet on board with, and may miss important information. As far as Zyrtec. For myself I would not take this drug. I did not find any link listed with causing hyperthyroidism. However, it has a huge list of side effects, and there are other safer ways to manage allergy symptoms. You need to check with your MD about stopping it. For myself, I would simply begin cutting back and then going off over a period of three to four weeks. But I am not able to recommend what you should do about this. Hope this has been helpful. all the best, Emi

      • Kim says:

        Thank you so much Emi for your response. I found out at my last visit that I have Hypothyroidism. She gave me Levothyroxine 75 MCG daily. I’m not real happy with the side effects and so far I still have the same symptoms for seeing her in the first place. I have been searching online for alternative thyroid medicine and came across this. Have you ever heard of it?
        There is a great Natural Thyroid medication that I am recommending. It only has two ingredients, and no Microcrystalline Cellulose. It is a Relatively NEW PRODUCT by Westhroid, so make sure you ask your MD for it specifically, as the OLD WESTHROID still has ingredients that have caused many problems. It is called: WP THYROID. That stands for WESTHROID PURE. The added inactive ingredients are clean: inulin from chicory root and Medium Chain Triglycerides from coconut. IT does have some Lactose in it as this comes in all porcine powdered Thyroid, yet we are told that its form is hypoallergenic. People who are Lactose intollerant seem to have no problems with it.
        I quit taking Zyrtec and am now drinking daily 2 table spoons of raw honey, 2 table spoons of apple cider vinegar with a dash of cinnamon mixed with hot water for my allergies. It also helps alkaline my system, so no more acid reflux. Thanks again, Kim

  38. Julia says:

    Thank you for posting on this topic and responding to the many comments! I grew up organic/natural in the US and I find it immensely frustrating and disturbing that so little information (particularly impartial scientific study-backed info) is available on the ever-increasing number of synthetic or supposedly ‘naturally derived’ additives/fillers/ingredients in well, everything. I try to live a life in which everything I use (from furniture to cleaning products to personal hygiene to consumables) is made from materials I know to be safe and would feel comfortable eating. Very difficult and expensive, and of course I cannot avoid all synthetics unless I wish to go without electronics.

    I am not a big fan of EWG or most similar sites because they don’t provide much information. My undergraduate background in chemistry and biology only goes so far without research on all these new compounds. At this point, I have decided to err on the side of caution; if I can’t find good research supporting a compound’s safety, I try to avoid it completely. I would love to see some lists of ‘most likely safe’ products like Dr. Bronner’s Soap compiled by people who think like you and I.

    Can I also say how very much it annoys me that only food and cosmetics list ingredients? I need to know what EVERYTHING is made of. And don’t get me started on all the deceptive marketing strategies and euphemisms, such as ‘non-toxic soy foam’ and ‘avocado butter’ (aka hydrogenated avocado oil), respectively.

    • Emi Miller says:

      Hi Julia, Sorry this is so late. Some of the posts do not register in the regular comment section, and I only find them much later! Thank you for posting. Yes, we need to know what is in our world… what toxins are about. I am a big fan of EWG. I don’t know if you have seen their new research on what chemicals are in “YOUR” water? They have incredibly looked into each and every (almost) zip code, and when you enter ‘YOURS” you can instantly see what toxins are above the safe limits, and they are NOT LISTED in “YOUR” water quality report! — Check it out, and then say a big thank you for all of the effort that EWG has put in to keep us all safe and informed. They have limited resources, and have done more that any other organization that I have found. — EWG Tap Water Database: https://www.ewg.org/tapwater/#.Wv8nbi-ZPOQ — all the best, Emi

  39. Emi Miller says:

    Hi Emi, My name is LaNae. I called you today @ 5:15 EST. I found your website and was very interested in your article about Micro crystalline cellulose! I need to get some medicine compounded and this is the ingredient that one particular compounding pharmacy uses. Can you tell me an alternative for the inactive ingredient if NOT using the MCC? Another compounding pharmacy uses Methyl Cellulose (psyllium husks). Is that OK or not harmful??

    I could ask for what ever ingredient that you would suggest as an alternative to the MCC.

    Thank in advance for your time and consideration.

    Peace, LaNae


    Hi LaNae,

    Thanks for writing. I recommend using organic coconut flour as the filler with compounded medicines, if your MD will agree to write the RX that way. I also recommend that your RX state that these capsules, be used: Capsuline Clear Geletin Empty Capsules — Link below….



    Vegetarian Capsules unfortunately are made from wood pulp… and this is NOT a vegetable source as we think of it, and wood is not absorbed…

    HPMC — Hydroxypropylmethylcellulose — is derived from pure cellulose of either pine or poplar, AND Not Digestible.


    Hope this helps,

  40. Jennifer says:

    Doesn’t the article address the use of nano-sized microcrystalline cellulose, and not microcrystalline cellulose in larger particle size? I do believe you are confusing those reading that it is the substance that is a danger, when it is actually the substance SIZE that is the problem.

    • Emi Miller says:

      Hi Jennifer, Yes, it is nanoparticles, and yet the problems exist with both micro-and nano particles. Here is one research article for you, showing that micro-particles penetrate through the skin into the dermal layer. As yet there are not many studies available online about this, but this one should give you pause. For myself, I err on the side of caution always. We simply are playing with things we know little about. And taking wood pulp which cannot be used by our cells into our bodies in micro particulate size makes no sense to me, and is bound to cause inflammation as our body tries valiantly to surround and wall it off. hope this is helpful to you. — Emi https://www.ncbi.nlm.nih.gov/pubmed/21699089

  41. Jessica says:

    Hi, I’m buying some supplements but most have Silicon Dioxide, Microcrystalline Cellulose or Magnesium Stearate. I was already avoiding Magnesium Stearate but have just seen that the other two might be harmful too. Which one would you say is less harmful to be found in supplements? Silicon Dioxide or Microcrystalline Cellulose? Cheers.

    • Emi Miller says:

      Hi Jessica, Yes this is a problem for sure. You did not tell me what kind of supplements? Do you mean vitamins? Do you mean a particular vitamin or mineral or herbal supplement? So I am in the dark, yet going to recommend a newish children’s chewable vitamin that has none of those ingredients, but has some of the best sources of vitamins that I have found, as well as fish oil as a source of Omega fatty acids, and vitamin D3, as well as methylcobalamine for the source of B12. And as for choosing a children’s chewable? After 30 years of watching the field of supplements go from megadoses back to minimal doses due to problems every time we tried to flood the body with dosages that it could neither process nor eliminate, for myself I have come to the conclusion that the best practice is to find good local sourced Organically grown produce, and eat this plus humanely raised and humanely killed Organic and locally farmed animals as much as possible…with a focus on whole foods being the first source of all of our vitamins and minerals, and if needed adding children’s chewable vitamins. This will change of course according to personal condition, and then it would be good to seek sound advice from a knowledgeable practitioner. Here is the name of the vitamin I currently like: “SMARTYPANTS Kids Complete Gummies with Multivitamin + Omega 3 + Vitamin D” As for dosage, the amount set for older children I feel is sufficient, with a diet that I would be happy to help you establish, based on your physical condition and needs. Hope this was helpful. — Emi

      • Jessica says:

        Thanks. They would be mainly Vit D3, K2, B12, Omega 3, Magnesium, Iron, etc.. but I’m vegetarian, so no gelatine for me. After much research I found some of these (D, K, Omega 3) in drops, so no added fillings.. will give them a try, and begin to substitute what I can for drops. But anyway, in your opinion, which would be the less harmful filling: Silicon Dioxide or Microcrystalline Cellulose? Cheers!

  42. Adie says:

    You do know that our bodies can’t digest cellulose, right? Like, that’s a well known fact. True that it’s made of glucose, but we don’t have the bacteria in our guts that can digest it. We also don’t have the gut to digest it.

  43. Sue says:

    Wow I wish I had the time to read all of the comments, and your replies are excellent. Since my son was born without a thyroid gland we have used every option of thyroid medication. Thyroid extract works best but the poop hit the fan when he started to fail badly and was diagnosed finally with sarcoidosis. To cut a long story short I finally tripped across the information that microcrystalline cellulose is implicated in another systemic granulating disease – agiocentric systemic granulomatosis. In the right light and after a bath and massage , granulations could be seen all across his abdomen and at the time he was severely emaciated. It took ages to arrange to have the filler in his compounded thyroid meds changed from MC – the recommended glycine made seizures worse, but we now use organic white rice flour and it seems to work fine.

    • Emi Miller says:

      Hi Sue, I am happy you took the time to write! Your response was cut short, however, and if you feel so inclined you can re-send it to us! — all the best, Emi

  44. Misha says:

    Hello Emi,

    Are there any prenatal vitamins you would recommend that are free of these harmful fillers? Thank you,

    • Emi Miller says:

      Hi Sarah, I think Blue Bonnet has a pretty good pre-natal vitamin. Not too heavy in the amounts. No one of the products on the market is ‘perfect’… but this one is among the best I have found. I don’t recommend products that say they are ‘food based’, as they don’t say the (necessarily) the food is GMO free, or Organically raised, and also I have heard that the amount of active vitamins vary.So check out Blue Bonnet Early Promise Prenatal Multiple Vitamins. There may be others you feel better will suit you and your baby’s needs!

      A Word of warning: Be careful not to get too much Folic Acid and B12 Vitamins. New research has shown a connection between high levels of Folate and B12 and autism. — I prefer less vitamin products and more vitamins and minerals (and proteins/carbs/good fats) from a healthy organic diet. Unless the mother to be is deficient. We have come to rely on pills, forgetting that moms have only had vitamin pills for a few short decades, and birthed healthy babes for thousands of years!

      “The study found that children at greatest risk of autism were those born to the mothers who had high levels of both folate and vitamin B12. These kids were about 17 times more likely to be diagnosed with autism than the kids born to women who had normal levels of both nutrients.” https://www.livescience.com/54711-autism-risk-linked-to-high-folate-levels.html

      *I am making an addition to this post: Please also know that for most of my patients who are pregnant I have hardly ever recommended a Pre-Natal Vitamin. I feel that they are too strong. Some research has concluded that women who are on them early in their pregnancy have had a greater risk of miscarriage. According to Eastern Medicine this makes some sense, when looking at Yin and Yang… The vitamins are highly expanding… and the directional energy needed for maintaining pregnancy is concentrating first. So I have recommended — for healthy women — whose lab work shows they are not out of balance, that they supplement a balanced, seasonal, organic diet with a children’s chewable. The one I am currently recommending is: Yummi Bears Organic Multi-Vitamins. They have the Folate and B12 as Methyl forms, and other good things as well. I also recommend these for children, and adults, but when they are in need of an immune ‘boost’, or during illnesses only. Here is the link: https://heronutritionals.com/brand/yummi-bears/ Hope this helps!

  45. Sam says:

    Hi Emi,
    I’m pretty confused! The form of folate/folic acid is NOT bio available in the Blue Bonnet prenatal-nor is the B12 (toxic cyanocobalamin) ?? Both very harmful! There is a big difference between these forms and the bio available forms. So the opposite holds true here, methyl folate IS very much needed in most pregnant women who do NOT break down folic acid due to ferric insufficiency (MTHFR). Same goes for B12-it CAN show very high in serum levels but could actually be dangerously low in the body because it is not being broken down properly. Cyanocobalamin is TOXIC and should never be the form of B12 to take. Depending on genotypes the better forms are Methylcobalamin or hydroxy and adenosyl cobalamin. Much safer:)

    • Emi Miller says:

      Hi Sam, I prefer to get B12 from sources such as meat, eggs, cheese and dairy products. As far as the Blue Bonnet Pre-Natal goes, yes I agree, and have waited a long time for a better alternative! The only one I found with methy form of B12 is formulated with microcrystalline cellulose! However, here is my take: with my family and patients I recommend (believe it or not)children’s chewables during a healthy woman’s pregnancy–which will be watched all the way through. It seems that we are growing babes very well with an organically raised diet, w/plenty of all the good things, proteins, appropriate grains and milks; seasonal fresh veggies and fruits, moderation in sweets, very low chemicals. I now am choosing an organic, chewable Children’s multi-vitamin: ORGANIC YUMMI BEARS COMPLETE MULTI-VITAMAN–Contains FOLIC ACID FROM Organic lemons; B12 Methylcobalamin. Is this enough for every pregnant mom? Maybe not, but for most of us I believe yes. I have never been a proponent of daily vitamins, but use them to help prevent or during illness, along with herbals. Hope this helps. This vitamin company with their new organic chews call themselves, Heros… And they are true “heroes” in my book!! I recommend them for all of us — Check out the Organic Yummy Bears Multi-Vits — https://heronutritionals.com/brand/yummi-bears/

  46. Sam says:

    Please PLEASE let your readers know of this VERY IMPORTANT DIFFERNCE between these forms of B vitamins. YES folic acid SHLULD be avoided and so should cyanocobalamin but NOT the bio available “true” forms of these vitamins because they are CRUCIAL for development of the fetus. That article is “dated” information and can misguide many people reading it. Thanks again:)

    • Emi Miller says:

      Hi Sam, Thank you for posting about the difference between cyanocobalamin and methylcobalamin. We had no idea that B12 was formulated with Cyanide, and we have been taking this for so many years! Fortunately vitamin companies are moving fast into the more natural form of methylcobalamin into their vitamin products. However we should also note that studies have been done on whether the sublingual route was superior to the oral route, and the results are in that both of these methods of ingestion yield equal results. And one step further, it seems that we must take not just B12 alone, but in a complex to be sure that it is absorbed, and also that we must take the vitamin complex with a protein food, preferably, meat, eggs, cheese and dairy. It has been a huge problem for the elderly, and many will need to have ongoing injections of B12 in order to keep their levels up. For vegetarians this has always been an issue, for though some amount of B12 will be absorbed without animal food, it is more difficult. Vitamin B12 is naturally found in animal products, including fish, meat, poultry, eggs, milk and milk products, and is not present in plant foods. It is in fortified cereals, yet presently in the cyanocobalamin form. Hope this helps!

  47. Elaine Pratt says:

    I have had 2 prescriptions, one a natural thyroid medication and the other a blood pressure med. Both caused terrible headaches, tight neck muscles with a lot of pain. After investigating the inert ingredients, the common one is the Crystalline Cellulase. The only way that I knew the thyroid medication was causing this problem was it went unavailable for a while. My dr. ordered a compound. All of a sudden, the headaches and muscle problem disappeared. I went back on it after it became available again. The side effect came back. I just had the same problem with a blood pressure med and I suspected it was a filler. I stopped it..changing to another, and in 2 days the side effect was gone.

    • Emi Miller says:

      Hi Elaine, Your story is pretty clear: you have a definite reaction to Microcrystalline Cellulose. Thank heaven you were able to figure this out. I know there are many, many thousands of people who have not had this information and are suffering as you were. Thanks for writing in! I hope your experience will be of service to others!

  48. Yvette B. says:

    Hi Emi,

    I was recently recommended to take K2 (MK4) powder as a preventative measure for osteoporosis.

    I’d like to take up to 45 mg (45,000 mcg) per day. (Japanese and U.S. studies have recently cited that it helps prevent bone fractures in conjunction with calcium and vitamin D3.) Using the company’s guide, I’d have to take 8 servings (based upon each white spoon supplying 6 mg or 6,000 mcg of pure MK4) per day.

    However, I’ve calculated based upon what I’d need to take, that, that would be approximately 450 mg of microcrystalline cellulose which is 0.450 grams (54 mg per serving x 8 servings = 432 mg). (I’m told the powder is mixed with fillers to prevent melting during shipping.)

    Are servings this high generally unsafe? What could some of the potential long-term side effects be of using this particular supplement?

    Thanks in advance!

    Yvette B.

    • Emi Miller says:

      Hi Yvette, and thank you for this question. I am sure that you are doing all you can do in the rest of your food and products and exercise to help to build stronger bones. As you have probably read, I am not a fan of Microcrystalline Cellulose, in any amount, and so I would not take this product, nor recommend it to my patients, or to you. I hope this has been helpful.

  49. David says:

    Emi I am so impressed you managed to work this out. I struggle so much with microcrystalline cellulose, and have polluted my body with it after taking supplements for years. Whenever I take something that contains it now, i feel these nanoparticles in all my joints, my body goes into a fever response to try and rid itself of them. This will last a few days and then those which havent been excreted I feel are stored away in various regions especially feet. The presence of these particles is again made clear when I have caffeine which causes redistribution. Do you have any idea of an effective method of clearing? Im thinking exercise post caffeine, but its very slow. Many thanks for your response.

    • Emi Miller says:

      Hi David, One way to help the body detoxify is by drinking Miso Soup. I don’t know if you have heard about the value of Miso in purifying the body of even cancer. It works to help us when we are fighting colds and flues. Toxic particles are flushed from the system. It even attracts radioactive particles osmotically and flushes them out of our body. Check this out: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695331/

      Yet we do not want powdered Miso. It has to be in a paste form, to keep the living part of it active. My favorite for cleansing is: Miso Master, Brown Rice Miso. It comes in the refrigerated section of health food stores. There are several kinds. Try to get the Brown Rice Miso. You can get it online. Yet stick to one cup a day for three-four weeks for cleansing: DO NOT EVER BOIL. Don’t add it to a boiling pot of chicken soup. It will kill the living enzymes and vast bacterial culture. Instead simply put it into a cup and pour hot water on top, and stir and drink. And, it is very salty. So for those with kidney/heart/blood pressure issues, caution is advised. Taking 1/2 strength, and every other day. And for everyone, using daily should only be for three weeks.Except for cancer, then please check with your practitioner as to how often to take it and for how long. Three times a week in Winter is good for helping to avert colds and flues, and if one gets a cold or flu increase to 1 cup daily. Then, unless one is in a cleanse, or ill, it is not needed in Summer, but can be enjoyed occasionally as the Miso Master’s White Miso. Hope this is helpful.

  50. Di Teague says:

    Im in dire need of a pure liothyronine as im hypersensitive to fillers. Cannot take t4 in any form at all. Can anyone help advise. Without it costing a ridiculous price

    • Emi Miller says:

      Hi Di/Aztec, I understand your difficulty. I have a question for you. Everyone has T4 naturally occurring in their bodies. So it seems that you should be able to handle T4 == if it were in a natural form, such as Desiccated Thyroid. You may have been reacting to the fillers or coloring agents in the kind of T4 you were taking. YES your doctor may have said that your body ‘Is not able to use T4″ Yet this means that your body cannot convert T4 into what our body needs, which is T3. It doesn’t mean you can not take any. It means you cannot take a medicine that is made ONLY OF T4. It means you need to take a medication that has T3 in it. And the Natural forms of Thyroid, which come mostly from pigs, and also from cows, contains BOTH T3 and T4 and so you will be able to take this. It works for those who can not take plain T4 Medications!! This is good news!!!

      Please ask your Dr. about taking: NP THYROID BY ACELLA. This is the most natural form we have right now, that is pharmaceutically titrated.

      Go To “Prescribing Information on THIS LINK HERE: https://npthyroid.com

      I have NOT found a better source of plain T3 for you out there. The Inactive ingredients in Cytomel consist of calcium sulfate, gelatin, corn starch, stearic acid, sucrose and talc. I am thinking that the T3 alone is too strong for you alone. Many people react from taking the only T3 form.

      Please don’t think you can’t take a Natural Desiccated Thyroid. It has T3 in it, along with a natural combination of T4.

      What’s the big deal about natural desiccated thyroid (NDT) like NP THYROID BY ACELLA? Unlike synthetic T4-only meds which have been a big problem for so many patients (Synthroid, levothyroxine, etc) …desiccated thyroid is Natural–and gives you exactly what your own thyroid would be giving you: T4, T3, T2, T1 and calcitonin.

      Here are the fillers in Acella:

      ingredients are calcium stearate, dextrose (agglomerated) and mineral oil.


      DON’T BE DISCOURAGED. I think you have misunderstood your M.D. I believe you most certainly can take T4 == if it is in a NATURAL FORM WITH T3 == with NO harmful fillers. Acella NP Thyroid may work very well for you. You have to find just the right dose. If your MD is not familiar with how to change you over from T4 to Natural Desiccated Thyroid… here is a CONVERSION CHART which shows you the dose you were taking of T4, and how to take the new Combination T3 and T4:


      I hope this is helpful. You can copy this note and take it to your M.D. and see what he or she says. Let me know! Emi Miller, R.N. HN-BC

  51. Di Teague says:

    Failure. I need pure t3 and im fine. I have been on t3 only for years and it suits me and is a life saver. I have a compounding small batch but need a back up plan. I did well on perrigo but the others have too many fillers. I was left untreated and misdiagnosed for years untill i went on t3 only. I have no thyroid left and a tiny bit of t4 which my body makes. I need a compounding pharmacy who can make me liothyronine with minimal fillers only
    It is out there

    • Emi Miller says:

      Hi again, Di Teague, Perhaps you can check in with Women’s International Pharmacy. They are well known for compounding with minimal ingredients. Contact them at: 800-279-5708. After checking with them, letting them know your needs, then your M.D. will need to call in your prescription. I am sure there are many other compounding pharmacies you can try, yet I have researched this pharmacy and so offer it to you, yet no pharmacy can meet the needs of everyone, so check with them and see. I hope this is helpful.

  52. I developed a horrible allergy to it when I moved from Los Angeles to the High Sierra, where we’re surrounded by trees. It took me more than a year to figure out I was allergic to the wood pulp, aka MCC, in my pills (as well as the trees!) Like most of you, I now read the inactive ingredient list with a fine tooth comb and often have to resort to buying RX from compounding pharmacies or even from foreign countries that don’t use it. Most pharmacists and physicians are clueless, but my biotech bro was a big help in deciphering the madness. I now travel with a stash of prednisone–just in case I accidentally ingest MCC and get a systemic rash that often involves hospitalization. The predisone (10 mg in one dose–like you’d take for an accidental brush with poison oak) is very effective at stopping the rash from spreading. Best thyroid for me without it is WP Thyroid, but they routinely run out so best to order a few months worth.

    • Emi Miller says:

      Hi Carole, Thank you for this post. I am sorry that you have had to experience severe reactions to fillers in your medications. As far as the WP Thyroid shortages, there is Acella NP Thyroid that you may want to look into. It is not perfect for it has mineral oil in it. I have called Acella and received a reply that states it is used in very minimal amounts as a lubricant in processing, and is not placed directly into the desiccated. Until you can get the WP thyroid it may serve you. If you find another desiccated thyroid source, please let us know. — I hope this is helpful, Emi

  53. Tammy says:

    Hi my name is Tammy I have just started taking a carb blocker by Nutrilite the first ingredient is Microcrystalline cellulose, stearin acid,silicon dioxide,sodium carboxymethycellulose,Methylcelluloe,Glycerin,Carmaube wax…. but I was told it was safe , that doesn’t sound safe to me, something told me to read the ingredients, is this really safe to take?

    • Emi Miller says:

      Hi again, Tammy. This first letter of yours popped up second. 🙂 Yet I will also briefly answer. As you have read I am not in favor of Microcrystalline Cellulose period. So I would not use or recommend this product. Yet as you will read in my last reply to you, please consider not trying to block your body from absorbing carbs. Find and stick to a wholesome, organic, seasonal, and as local as possible diet. — with all the best, Emi

  54. Tammy says:

    Is there a holistic way of carb blocking, do you have any suggestions?

    • Emi Miller says:

      Hi Tammy, Well this is a question that has a definite holistic answer: Each and every kind of nutrition that humans have evolved with has sustained our bodies for millennia. And, as this is true, each one is needed for our bodies to function, to maintain our physical health, to prolong our lives. Only in our ‘Scientific’ civilization has humanity been able to intellectually think about changing our diets to suit the ‘Current Day Thoughts’ about what is ‘Best’ for us. And, as we have all seen time by time and time and again… each and every diet fad has its day and then 5-10 years later we read about the harmfulness that it caused those who chose to be believe in it, those who jumped onto that particular band-wagon. And then that ‘Best’ becomes not good, and another ‘Best Diet’ comes forth, and everyone jumps on board… because they have heard, or read, that some experts believe it will promote healing, weight loss, long life. And so it goes. And so it goes. You may not be old enough to remember the switch back and forth from butter to margarine, from low fat to full fat, from high Vitamin A and too high doses of Omega 3s and more… everyone runs…. toward…. and then runs away… and yet believes that the ‘Latest’ is surely the ‘Best’. Why? Here is another example. Carb Blocking. First of all, what kind of carb are you trying to block? For carbs are everywhere. And we have evolved with them as a primary source of our body’s energy system. This is almost amusing, except that it is sad, and very sad, in that people will spend their money and many will harm their lives by trying to block carbs, no matter how ineffective, or unnecessary this is. What you may be seeking is a reduction in sugar, or calories. And the best way and the healthy way to do this is not with a pill, ever… but with a sound nutritional plan that you keep steadily to. A balanced diet with natural, ordinary, locally grown and chemical free as possible. Daily adherence to such a diet will certainly benefit you today, and tomorrow, and all of your life. — I hope this was helpful. Emi

  55. Rose says:

    Hi Emi,

    I have been trying to buy my medication in some of the companies that you recommended me but they have a many orders and it has been impossible to get the medication with them.
    I read in the comments above that you recommend to use organic coconut flour or white rice as a filler. However, here in Australia, I could find a pharmacy which uses fillers such as turmeric, maca powder and tyrosine. I am not sure about what of these could be better, there is a lot of information on the internet and everything is very confuse. I read that turmeric can lead a estrogen dominance (I must very careful, because with 41 years old, I am going through my post-menopause) and something bad related with maca but to be honest I cannot remember.

    Could you recommend me, one of these fillers?

    Thanks a lot for your help

    This is the link about estrogen dominance and what avoid.

    • Emi Miller says:

      Hi Rose, I hope you have found an answer at this point, that works for you. Yet if you are still in question, what I recommend to my patients is to buy Organic Rice Flour, or Organic Coconut flour, and hand it to the compounding pharmacy, and tell them that you have sensitivities to many fillers, and could they please use this for you. Let them know that you will be happy to bring more in to them every two months. As for Maca powder, it has properties that can interfere with thyroid function, and I would avoid it if possible. If you have thyroid problems, you may want to be careful with Maca. It contains goitrogens, which act like estrogens, and these compounds are more likely to affect you if you have problems with your thyroid gland, and of course your own estrogen production. Not likely in small amounts, but why take a chance?

      https://www.webmd.com/vitamins/ai/ingredientmono-555/maca — Hope this is helpful.

  56. Rose says:

    Hi Emi,

    I have been asking in some pharmacies, and they are offering me many fillers. However, one of them, catch my attention, is magnesium glycinate.

    At the same time they add a compound to slow release Thyroid Extract, called Methocel E4M, which is also diary and gluten free.

    Do you know something about these?

    Thanks a lot

    • Emi Miller says:

      Hi Rose, Methocel E4M is made from cellulose, and we don’t know the source of the cellulose, is it from wood pulp? We don’t know. Also you can simply choose to take the thyroid several times a day, for example in the morning take 2/3 of your dose, and around 3 pm take 1/3 of your dose. As far as the magnesium glycinate, here is an article that may help you understand and decide if you want this filler or not: https://naturalcalm.ca/about-magnesium-glycinate-glycine/. I hope this is helpful.

  57. Darlene says:

    Good morning. I found your information on microcrystalline cellulose very interesting. I recently purchased Bio-X4 as a dietary supplement to help me loose weight…I noticed the label had the following info, “Other ingredients: Vegetable Cellulose (capsules), Microcrystalline cellulose, Stearic acid, Silica.” With the exception of the word “vegetable” everything else sounds foreign, however, I thought I would ask you for your opinion.

    Do you think this is safe to digest or do you have any other supplements you would recommend to a recent post-menopause woman who can’t seem to loose weight the way I used to?

    • Emi Miller says:

      Hi Darlene, For sure cellulose is questionable. Companies are using the word when their products have wood pulp in them. Very deceptive in my opinion. And of course this can lead to weight loss as the product cannot be absorbed. But then you face loss of nutrients and this is troublesome to me. Same for the Microcrystalline Cellulose, and the Stearic acid does not say, Vegetable Source. I would rather coach you on a good diet plan, and would be happy to do so if you want to email me directly and set up an appointment to review your health needs and concerns. Thank you for writing and I hope this was helpful.

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